1
Depression
2
Patient
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Science
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Pipeline
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About
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Get Involved

Are you looking to get involved with Aingeal? Simply get in touch through the form below and a team member will get back to you.

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By the Patient.
for the Patient.
of the Patient.

Patient first
It is rooted in our company vision to put our patients first. This starts with involving them from the beginning of the drug discovery journey.

At the end of the day, this new drug is for you and your loved ones. You should have a voice in shaping, developing, and applying your own treatment. Help us help you.

How We Make New Drugs

Get Involved
Overview

Our patients have the potential to enhance the quality and efficiency of clinical trials by providing their input, ideas and feedback during this journey.

Here is an overview of our drug development process and how your input matters.

discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage *
discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage *
discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage *

Discovery Stage

Discovering, testing, and refining the compound.

Brief overview

First, we determined the drug target, or the biological molecule that we're going after to modulate its function with a drug. In our case, we're targeting a synaptic protein called PSD-95 to boost BDNF activity.

Once we've collected the evidence to show efficacy and safety, our next step is to ask the FDA for permission to test our drug in humans. This is done through an IND, or Investigative New Drug application.

Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 *
Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 *
Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 *

Phase 1-3

Clinical trials: the first time our drug is given to humans.

Patient Engagement

In Phase 1, we address the question of: what dose can we safely and effectively give our drug to people?

In Phase 2, we answer: at the dose we picked in Phase 1, does it work? Is it safe for sure?

In Phase 3, the question is: does it really work? Is it better than what we already have?

Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review *
Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review *
Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review *

Regulatory Review

Filing for and receiving final approval.

Patient Engagement

After successful clinical trials Phase 1-3, we apply for FDA approval through an NDA, or New Drug Application. The Center for Drug Evaluation and Research within the FDA will then decide if we can make the drug available to the people.

Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval *
Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval *
Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval *

Post-Approval

After approval of our compound.

Patient Engagement

This stage, also known as post- approval pharmacovigilance, determines: how'd our drug do? Looking at various populations, how well did it work? Are there any rare or long term side effects?

It's critically important to study the actual impact of our drug- did we help our patients? Our mission is to fix your brain- this is where we'll find out if we accomplished it.

How We Make New Drugs

Get Involved
SHAPE YOUR OWN FUTURE * SHAPE YOUR OWN FUTURE * SHAPE YOUR OWN FUTURE *
SHAPE YOUR OWN FUTURE * SHAPE YOUR OWN FUTURE * SHAPE YOUR OWN FUTURE *
SHAPE YOUR OWN FUTURE * SHAPE YOUR OWN FUTURE * SHAPE YOUR OWN FUTURE *
Patient Engagement

Our patients have the potential to enhance the quality and efficiency of clinical trials by providing their input, ideas and feedback during this journey.

Here is an overview of our drug development process and how your input matters.

Discovery Stage

Discoverying the initial drug compound.

discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage *
discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage *
discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage * discovery stage *
Patient Engagement

First, we determined the drug target, or the biological molecule that we're going after to modulate its function with a drug. In our case, we're targeting a synaptic protein called PSD-95 to boost BDNF activity.

Once we've collected the evidence to show efficacy and safety, our next step is to ask the FDA for permission to test our drug in humans. This is done through an IND, or Investigative New Drug application.

Phase 1-3

Testing and refining the compound.

Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 *
Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 *
Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 * Phase 1 -3 *
Patient Engagement

In Phase 1, we address the question of: what dose can we safely and effectively give our drug to people?

In Phase 2, we answer: at the dose we picked in Phase 1, does it work? Is it safe for sure?

In Phase 3, the question is: does it really work? Is it better than what we already have?

Regulatory Review

Filing for and receiving final approval.

Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review *
Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review *
Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review * Regulatory review *
Patient Engagement

After successful clinical trials Phase 1-3, we apply for FDA approval through an NDA, or New Drug Application. The Center for Drug Evaluation and Research within the FDA will then decide if we can make the drug available to the people.

Post-Approval

After approval of our compound.

Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval *
Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval *
Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval * Postapproval *
Patient Engagement

This stage, also known as post- approval pharmacovigilance, determines: how'd our drug do? Looking at various populations, how well did it work? Are there any rare or long term side effects?

It's critically important to study the actual impact of our drug- did we help our patients? Our mission is to fix your brain- this is where we'll find out if we accomplished it.

01
Depression
02
Patient
03
Science
04
Pipeline
05
About
Get Involved

Are you looking to get involved with Aingeal? Simply get in touch through the form below and a team member will get back to you

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.